6 Exciting KPV Peptide Benefits for Your Health
Despite being relatively new in the biohacking space, the KPV peptide offers some impressive benefits with mounting research to back them. Whether you’re dealing with inflammation, want to improve your skin health, or are managing gut issues, the KPV peptide could be the answer you’ve been looking for.
What is the KPV Peptide?
KPV is a tripeptide containing lysine, proline, and valine. It occurs naturally in the body, specifically in a hormone called alpha-MSH, which makes it an alpha-melanocyte-stimulating hormone. This class of hormones has anti-inflammatory and immunomodulating properties, so KPV peptide is especially helpful with both inflammatory and auto-immune conditions.
KPV, like other peptides, acts like a hormone. It sends signals and messages from one tissue to another through the blood, using biological messengers. You can get KPV peptide supplements as an oral capsule, cream, or injectable. Depending on how its administered, it can help with skin conditions, gut issues, inflammatory conditions, and more. Since KPV peptide is so well researched, it’s often considered a great supplement for optimal wellness.
How Does KPV Work?
The method of delivery for KPV involves iontophoresis, a process that utilizes low-level current to facilitate the absorption of charged compounds through the skin barrier. By employing iontophoresis, KPV, along with other drugs, can be effectively driven deeper into the skin, thus bypassing the initial metabolism in the gut. This approach is advantageous as it enhances drug absorption and ensures efficient delivery of KPV for effective therapeutic outcomes.
Benefits of Taking KPV Peptide
1. Helps to Reduce Inflammation
One of the most well-studied benefits of KPV is its anti-inflammatory properties. Inside cells, KPV inactivates inflammatory pathways by interacting directly with inflammatory signaling molecules. It’s especially effective at treating inflammation in immune cells and epithelial cells. In studies, KPV has been shown to effectively reduce inflammation relating to colitis, tumors, and asthma via a variety of mechanisms.
2. Supports the Immune System
There’s a clear indication that KPV can strengthen the immune system. In studies, it appears that KPV stimulates the production of immune system cells. Multiple studies found that KPV could lower body temperature and even prevent fever. In another study, KPV helped to reduce the symptoms of inflammatory eye diseases and significantly reduced the inflammatory substances resulting from the diseases.
3. Improves Skin Conditions
KPV Peptides have been used to treat a variety of skin conditions. For example, one study found that the use of a topical KPV cream reduced eczema. In another study, the peptide was able to suppress the inflammatory response of the skin to contact dermatitis.
There may be a few ways KPV manages to improve the skin. One study found that the peptide acts as a natural anti-allergenic basophil-response modifier. Another reported that KPV was responsible for regulating the production of interleukin-10 by skin cells, which is a mechanism that prevents inflammation of the skin.
4. Safeguards
KPV occurs naturally in the hormone alpha-MSH, which is an endogenous peptide hormone, as well as a brain peptide. KPV peptide and alpha-MSH have properties that could have a therapeutic effect on strokes.
For example, one animal study found that KPV aided in the recovery of animals suffering from a stroke. In particular, multiple studies have reported success in providing KPV before and during ischemia, which is when blood flow is reduced to the brain. The research suggests that KPV may actually fight against ischemic brain damage by reducing the levels of proinflammatory cytokines in the brain. It may also help to reduce the size of dead tissue that results from ischemia.
5. Help Fight Nerve Damage and Aging
KPV actually protects against the effects of nerve damage because it is a C-terminal of alpha-MSH. That means it may actually be able to help fight aging, as well as various other nerve-related medical conditions. Studies show that it can protect nerves after spinal cord injuries, promote nerve cell growth, protect against ultraviolet radiation-induced apoptosis, and even has anti-scarring properties.
6. Promotes Healing
Like some other peptides, KPV peptide can actually speed the healing of wounds. Plus, since it fights inflammation, reduces infection, and has antimicrobial effects, it can actually lead to better cosmetic results in wounds. KPV treatment can provide smaller-than-normal scars, a lesser inflammatory response, and reduced scar prominence because it modulates collagen metabolism. KPV has also been shown to reduce the inflammation that normally leads to keloids, or hypertrophic scars.
7. Possible Cancer Impacts
KPV treatment has been shown to effectively reduce tumorigenesis and inflammation associated with carcinogenesis. Administering KPV prior to the onset of colon cancer could potentially serve as a preemptive measure to impede colonic carcinogenesis. While the exact mechanism behind how KPV decreases tumorigenesis remains incompletely elucidated, its ability to mitigate cancer development underscores its significance in cancer treatment.
8. Promotes Gut Healing
One of the most well-studied benefits of KPV is its anti-inflammatory properties. Inside cells, KPV inactivates inflammatory pathways by interacting directly with inflammatory signaling molecules. It’s especially effective at treating inflammation in immune cells and epithelial cells. In studies, KPV has been shown to effectively reduce inflammation relating to colitis, tumors, and asthma via a variety of mechanisms. Specifically, KPV significantly decreases inflammation in colitis by inhibiting proinflammatory cytokine synthesis and secretion. This action stops proinflammatory mechanisms in both intestinal epithelial cells and immune cells. Moreover, KPV can directly interact with immune cells to reduce inflammation, showcasing its efficacy in addressing gut issues such as ulcerative colitis and inflammatory bowel diseases.
9. Antimicrobial Effects
KPV peptide demonstrates remarkable antimicrobial effects by inhibiting the growth of two major pathogens, S. aureus and C. albicans, as highlighted in studies by Luger TA, 2007, and Böhm M, 2019. In one study, the significant inhibition of S. aureus colony formation by KPV showcases its potent antimicrobial activity. Additionally, KPV’s ability to combat inflammation, reduce infections, and specifically target these pathogens not only accelerates wound healing but also leads to improved cosmetic outcomes, including smaller scars and reduced scar prominence. By modulating collagen metabolism and curbing inflammation associated with keloids and hypertrophic scars, KPV emerges as a multifaceted peptide with profound antimicrobial effects that contribute to enhanced healing and aesthetic results.
Are There any Notable Side Effects of KPV?
KPV is a naturally derived peptide claimed to have no significant side effects, as evidenced by animal studies where its oral, intravenous, subcutaneous, and transdermal administration showed safety and efficacy. However, there is a cautionary note on the potential for interactions with other medications, stressing the importance of consulting an experienced Functional Medicine practitioner when using KPV or any similar peptides.
How
How to Take KPV Peptide
You can use the KPV peptide for a variety of benefits, whether you prefer a topical cream, injection, or oral supplement. Although the topical cream is best for most skin conditions, the oral tablets can offer KPV’s vast array of benefits. Whether you’re in search of anti-inflammatory effects or boosted immune system health, taking KPV can be a vital part of your wellness routine. Check out Kiya Longevity’s KPV Ultra oral spray and capsules today!
References:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403564/
https://pubmed.ncbi.nlm.nih.gov/18061177/
https://www.sciencedirect.com/science/article/abs/pii/S0022354917301740
https://medicinewithheart.com/blog/peptide-therapy-kpv-the-anti-inflammation-pro-healing-peptide/