By Brian James Rose
Melatonin is a miracle molecule that is required for the human body to function. It is made naturally by the human body. Melatonin is one of the most powerful, and versatile antioxidants. It is produced by the pineal gland in the brain. It can also be found in some other areas, including the eyes, bone marrow, and the gut. Melatonin is usually called the “sleep hormone,” as high levels can help to fall asleep immediately. Melatonin production reaches its high level in puberty and then continuously decreases its level as we grow older, resulting in the physically degenerative condition that is known as “aging”. Melatonin is an amazing and remarkable molecule, known as the master Hormone-Modulating molecule that can help to control the body’s aging clocks. Melatonin supplementation may assist the body and brain to maintain a youthful state. Three decades of research and a lot of practice in the field of immunology, oncology, biochemistry, and scientific evidence supports the belief of the people that discouraging vision of aging is a thing of the past. Melatonin is present everywhere in the biological world, from unicellular organisms to multicellular vertebrates. In the modern age, melatonin not only alters the way people view aging but also can alter the way people age. This fabulous molecule can add decades to people’s lives and enable them to live those years with a strong, healthy, and youthful body. Moreover, melatonin is one of the common dietary supplements that have gained much popularity around the globe of the world. When melatonin levels in the body naturally begin to decline, around age 45 years, then people must begin to take a specific quantity of melatonin supplements. For this purpose, it is commonly made synthetically in laboratories. Generally, it is available in the pill form, but also available in the forms which can be placed in the human cheek or under the tongue. That allows the melatonin to be absorbed in the human body directly. A recent study has proven that women produce less quantity of melatonin in the summer season when the days are too long and more melatonin in the winter season when the days are too short.
Melatonin can protect both the lipids and the proteins in the body against damage and can scavenge a few of the most harmful free radicals in the body such as hydroxyl radicals and hydrogen peroxide. Unlike all the other antioxidants, melatonin can diffuse into all cells and even crosses the blood-brain barrier to protect the delicate brain. Melatonin’s main and basic job in the body is to regulate the night and day cycles or sleep-wake cycles in the best way.
Top 15 best health benefits of Melatonin in the human body:
1. Role of Melatonin in Sleep
Proper sleep is necessary for human health and well-being. The human body needs to sleep as much as oxygen. So, proper sleep allows the body to refuel and provides the body’s cells a chance to repair and regenerate them according to requirements. As people age increase, the specific amount of melatonin produced by the body decreases, as a result, sleep disturbances occur. The adult requires 8 to 9 hours of sleep every night to allow for the completion of this best regeneration process.
Poor sleep can deplete the energy of the body, lower productivity, and increase the risk of different diseases including, high blood pressure, obesity, diabetes, immune-system dysfunction, and productivity in a lot of other body activities. Although poor sleep is a common issue it can have severe consequences. In that case, Melatonin is fruitful for the proper functioning of circadian rhythms. The circadian rhythm is the best and amazing human body’s internal clock that tells the human body about the proper time that when to sleep, and when to wake. At night time, in darkness, the pineal gland releases melatonin that causes the rate of your heartbeat to slow down and your body temperature to drop down. These physiological conditions allow your body for deep and restful sleep. The pineal gland also blocks melatonin release during daylight. That is a signal for the body that it is time to wake up. Melatonin also shortens the amount of time that is taken to fall asleep and improves the quality of sleep in children and adults. It has also become one of the popular supplements among people who are struggling to fall asleep.
Moreover, melatonin can also help with jet lag that is a temporary sleep disorder. Generally Jet lag occurs when the human body’s internal clock is out of sync with the new time zone. It is found that melatonin is remarkably effective and best at reducing the effects of jet lag in the human body.
2. Role in Aging Clock
Aging is the loss of the body’s natural ability to adapt to its environment. Aging is an ultimate disease because, as the body, ages increase it makes people more susceptible to different diseases. These diseases, in turn, cause the human body to age. In short words, the perfect and precise point in the human brain that controls how we age is called the “aging clock”. In that case, melatonin plays a key role in resetting this clock, health, and longevity in the human body. If people consider the human body as a rubber band So, when people are young and strong their bodies can easily bounce back from the force of this stress but as the age of the people increases they increasingly lose the ability to rapidly adapt to new situations, in short, people lose their resiliency. In that case like an old rubber band, it takes a much longer time to bounce back.
It is also considered that the pineal gland plays the same role in the bodies that the conductors do with an orchestra. The pineal gland regulates and harmonizes the functionality of a lot of parts of the body. The pineal gland also functions as the body’s aging clock. The pineal gland is also considered the master of circadian cycles and the miracle molecule that the pineal gland produces which is melatonin.
So, a young pineal gland, with the help of its Master Molecule, melatonin, sends a specific message of “youth” throughout the body, keeping the human body healthy and strong. Melatonin supplements in the aging subjects can easily restore pineal glands to their youthful, productive states, and restore balance to the body, which reverses the aging process.
3. Supportive for Eye Health
Adequate melatonin levels are much supportive for eye health. Because melatonin is rich in antioxidants that can easily help to prevent eye cell damage and keep your eyes healthy. Different researches have shown that the miracle molecule melatonin could be very beneficial in treating some specific conditions such as glaucoma and age-related macular degeneration. Melatonin is best to protect the eye retina, delay age-related damage, and preserve visual clarity. Moreover, melatonin also minimizes the severity and incidence of retinopathy that is an eye disease that affects the retina and can result in loss of vision.
4. Protect against diabetes risk
Melatonin protects against the risk of diabetes. Because it influences the blood sugar and insulin, which are key markers for metabolic health and drivers of different metabolic diseases, including diabetes. Melatonin has a nest protective effect over metabolic health and it can lower diabetes risk in the human body. According to the research, maintaining healthy nocturnal melatonin levels in the body can cut one’s risk for diabetes in half, as compared to those people who have low nighttime melatonin production. Melatonin can effectively minimize the risk for diabetes by interfering with insulin, a hormone that is much helpful for the cells to access glucose from the bloodstream, thereby regulating blood sugar levels. In this way, this miracle molecule protects against diabetes.
5. Protect against Alzheimer’s
Melatonin provides the best protection against age-related brain diseases, such as Alzheimer’s. For decades it is considered that Melatonin levels are associated with Alzheimer’s disease. Generally, People with Alzheimer’s contain much lower levels of melatonin in their bodies as compared to their age peers without this disease. And the decrease in the level of melatonin continues as the neurodegenerative disease progresses in the body. According to research, melatonin has significant neuroprotective capabilities, and it can help to prevent Alzheimer’s in part by slowing or stopping the accumulation of damaging amyloid plaque and other harmful proteins in the human brain. The supplemental melatonin may be much helpful to reverse the cognitive decline when Alzheimer’s disease is already present.
6. Protect against cancer
Melatonin is one of the best anti-cancer agents. One of melatonin’s most important benefits in health is in fighting a wide array of cancers. T-cells are one of the body’s primary cancer fighters. While cancer is a group of different diseases in which the body’s cells become abnormal and divide without any control. Cancer cells may invade nearby tissues and can easily spread through the bloodstream and lymphatic system to the other parts of the human body. Melatonin plays the role of the master regulatory molecule in that case.
Melatonin can suppress cancer cell and tumor growth along with the Inhibition of cancer metastasis. This molecule is the best booster for the effectiveness of cancer treatment and it can also reduce the severity of some side effects from radiation and chemotherapy during the treatment. Melatonin is a perfect molecule to prevent cancer from developing in the first place. Melatonin can help prevent hormone-dependent cancers, such as breast cancer and prostate cancer. Melatonin is a strong and best tool in the prevention of cancer in its role of strengthening the immune system that is the body’s natural ability to identify and destroy abnormal cells from the body. Melatonin can also hinder spindle formation that can potentially slow down cell division in the body. Apoptosis protects against cancer disease, and melatonin supports the apoptosis of cancer cells. In addition to the melatonin benefits for cancer survival, melatonin may also counteract the toxicity of chemotherapy treatment.
7. Helpful in Treatment of Stomach Ulcers and Heartburn
Amazing antioxidant properties of the miracle molecule melatonin are much helpful in the treatment of stomach ulcers and alleviate heartburn. For this purpose taking a specific quantity of melatonin, tryptophan, and omeprazole that is a common medication for acid reflux is helpful to heal stomach ulcers. Melatonin along with omeprazole is effective to reduce heartburn disease.
8. Reduce the Symptoms of Tinnitus
Tinnitus is a severe condition that is characterized by a constant ringing in the ears. It is often harmful in case, when there is very little background noise, like, people trying to fall asleep. Melatonin is suggested as the best treatment for tinnitus because of its positive effects on sleep and its vasoactive or antioxidant unique properties. Melatonin is perfect to improve sleep disturbance that is especially linked to tinnitus. Different studies on melatonin and tinnitus have revealed clearly that melatonin can help to ensure a good night’s sleep and also reduce the harmful and worst of tinnitus symptoms for a lot of people. According to research, sixty-one adults with tinnitus took almost three mg of melatonin before going to bed for 30 days. It helped them a lot to reduce the effects of tinnitus and significantly improved sleep quality.
9. Melatonin role in Sexuality and reproduction
Researches have shown that melatonin plays a vital role in the regulation of a lot of reproductive processes such as puberty, gonadal function, and pregnancy. Besides it, melatonin is also able to directly neutralize several free radicals and reactive oxygen and nitrogen species present in the human body. Melatonin is also helpful in restoring both male and female sex organs and drive to their youthful “peak performance” levels in the best way. According to Clinical trials, melatonin can prevent age-related deterioration of sexual organs, which has been linked to impotency, sexual dysfunction, lack of desire, and many more.
The pineal gland produces melatonin and even regulates the release of hormones that help all the new mothers forge a tight bond with their offspring. It is that specific bond that creates the maternal instinct that drives a mother to protect her young one. That is compulsory for the survival of species. These hormones also control the human sexual development process. Different evidence supporting a melatonin reproductive hormone focuses on the findings of an abnormal level of melatonin secretion in disorders of the reproductive system. Normal melatonin rhythm levels are also closely related to those of the reproductive hormones during infancy and mutually correlated during puberty.
10. Increase the Growth Hormone Levels in human
Human Growth Hormone is a specific type of hormone that is important to the growth of the human body and cellular regeneration. Moreover, it is also fairly safe and non-toxic for the human body. The human growth hormone is produced by the human pituitary gland. Studies revealed that the powerful molecule melatonin can make the pituitary gland, which is the organ that releases growth hormones in the human body. Lower HGH levels can decrease the quality of human life, and increase the risk of different diseases. On the other hand, higher levels of this human growth Harmon have also been linked to increases in the strength and muscle mass in the body. So, the melatonin supplement can directly enhance HGH production in the body. Good sleep is also beneficial to improve the HGH levels, as melatonin improves sleep quality so melatonin is much helpful to improve the level of Human Growth Hormone in the body.
11. Helpful in stress management and Seasonal Depression
Stress is a normal part of daily life. Stress is the body’s natural reaction to any change that needs a response. The human body commonly reacts to these changes with physical, mental, and emotional responses. Even people can experience stress from their environment, body, and thoughts. In the human brain, the hypothalamic-pituitary-adrenal system is activated, triggering the formation and release of the primary stress hormone. Corticosteroid that is released by the HPA, is involved in a vast range of physiological systems such as, stress response, immune response, carbohydrate metabolism, protein catabolism, etc. elevated levels of corticosteroids can be harmful to the human body, including the high level of stress. It can increase blood sugar levels, risk of diabetes, and damage the heart the body. Damage in the brain due to stress affects the ability to think clearly and retain information in memory for a long time. Melatonin supplementation, in that case, normalizes corticosteroid levels in human bodies. Taking melatonin not only protects against the negative aspects of stress by keeping corticosteroid levels in control.
But also works with endorphins, which is special stress-reducing, and pain-relieving chemicals produced by the immune system. Melatonin improves the effect of endorphins, by helping the body to withstand stress and promote a greater sense of general well-being in that case.
12. Helpful in Seasonal affective disorder
Seasonal depression is generally called the “winter blues” or seasonal affective disorder. According to an estimate Seasonal affective disorder is a common condition that affects almost 10% of the population in the whole world. This kind of depression is usually related to the alternation in the seasons and occurs every year around the same time. It could also be linked with the changes in circadian rhythm that are caused by seasonal light changes. Because melatonin plays an important role in regulating circadian rhythm, that’s why its low doses are often used to decrease the symptoms of seasonal depression.
13. Protect Against Treatment of GERD
Gastroesophageal reflux disease (GERD) is a disease that is caused by the backflow of stomach acid into the esophagus. That results in symptoms like heartburn, nausea, and belching.
Melatonin can block the secretion of stomach acids to protect against this disease. It can also minimize the production of nitric oxide, which is a compound that relaxes the lower esophageal sphincter, which allows the stomach acid to enter your esophagus. That’s why melatonin is commonly used to treat heartburn and GERD.
14. Protection to the Immune System
The immune system is one of the most important, intricate, and dynamic systems in the human body. It is specially designed to respond to protect the human body against the millions of external, unwanted bacteria, microbes, parasites, and diseases that can attack and destroy the body. T-cells play a vital role in immune system functioning and also produce a large number of such substances that regulate the immune response. Even a multitude of healthy, best, and active T-cells are compulsory for healthy survival. As the age of people increases, the thymus gland, which stores and controls T-Cells, deteriorates, causing the T-cells to become less effective for the immune system. As a result the immune system gradually breaks down, leaving behind vulnerable to the onset of disease. Some other factors also suppress and damage the immune system’s functioning by decreasing the number of active white blood cells in our bodies. A recent study shows that melatonin supplementation can increase the weight of the thymus, as well as the proper activity of the T-cells in the body. Clinical trials have shown that melatonin, the master hormone regulator works well to strengthen the body’s antibody response, which helps fight against different viruses. It can also improve thyroid function that in turn boost and support the immune system’s functioning and proper working.
15. Melatonin in weight loss
Researchers have indicated melatonin is beneficial for body composition and fat oxidation (burning) to lose weight. Melatonin can also increase the rate of metabolism in the human body. Melatonin simply exerts its effect on the weight of the human body by modulating the action of a lot of key metabolic homes such as insulin, ghrelin, and lepton.
Is it beneficial to take melatonin every night?
Melatonin is a molecule that the human body makes naturally, and its also used in a supplement form for different purposes. This amazing molecule is also believed to be fully safe. It is not a habit-forming molecule, and you will not become addicted to it. It can be easily used on a nightly basis without any fear of adverse consequences at all.
Does melatonin cause weight gain in the human body?
Researchers have indicated melatonin is beneficial for body composition and fat oxidation to weight loss. Melatonin exerts its effect on the extra weight of the human body by modulating the action of several key metabolic hormones including insulin, and ghrelin.
Can melatonin slow down the metabolism in the body?
Melatonin increases metabolism and improves the ability to lose weight instead of slowing down the metabolism in the body.
Is Melatonin helpful for Anxiety?
Melatonin is naturally produced by the human body. Melatonin Supplementation for anxiety can increase sleep quality, regulate circadian rhythm, and ease negative feelings that are associated with anxiousness.
Melatonin has a lot of health benefits for the human body. Melatonin the miracle molecule is the best and non-toxic supplement that can help people to fight against different diseases including fall asleep, especially in case of insomnia or jet lag, eye health, tinnitus symptoms, treat stomach ulcers and heartburn, increase growth hormone levels in humans, cancer treatment, and help with seasonal depression, etc.
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