Complete list of Peptide Manufactures

1.BOC Sciences

BOC Sciences is high-quality CDMO partner that accelerates drug development. They have an experienced team of experts and have cooperation projects with many well-known companies. They assist in process R&D, analytical development, synthesis, scale-up, or final product production for APIs or chemical macromolecules; they can provide high-quality solutions.

Peptide Manufacturing:

BOC Sciences has more than 20 years of experience in the synthesis and GMP production of peptides and peptide-related compounds. They specialize in production using liquid phase, solid phase, and hybrid synthesis techniques. As one of the largest peptide contract manufacturers in the world, they have 4 production bases and nearly 1,000 employees.

The advanced technical team of BOC Sciences has accumulated rich professional knowledge in the field of peptides and can develop more than 1,000 kinds of peptide compounds by combining SPPS, LPPS, and structural chemistry and fragment polycondensation methods, with a success rate of over 98%. Their peptide production bases are equipped with advanced peptide synthesis, separation and purification and testing equipment to ensure a stable commercial production process and are an ideal business partner for your GMP peptide needs.

Products:

They provide custom synthesis of peptides based upon requirements.

Contact details:

Address: 45-16 Ramsey Road, Shirley, NY 11967, USA

International: 1-631-504-6093

US & Canada (Toll free): 1-844-BOC (262)-0123

Fax: 1-631-614-7828

Email: info@bocsci.com

2. Creative Peptides

Creative Peptides is specialized in the process development and the manufacturing of bioactive peptides. They are dedicated to offering custom peptide synthesis, process development, Manufacturing as well as catalog products for customers in industry and research area. Creative Peptides is staffed by scientific teams with experts in the fields of peptide technology, antibodies, and synthetic chemistry. Their extensive expertise is translated into high quality products and world-class services to ensure the maximum satisfaction of the customers.

Products:

API Peptides

  • Angiotensin II Acetate      
    • Atosiban    
    • Bivalirudin
    • Trifluoroacetate     
    • Buserelin Acetate  
    • Deslorelin Acetate
    • Thymosin β15       
    • Triptorelin Pamoate           
    • Depreotide 
    • Vancomycin          
    • Teicoplanin
    • Ramoplanin

Cosmetic Peptides

  • Copper Peptide(GHK-Cu)
    • Acetyl Glutamyl Heptapeptide-3  
    • Palmitoyl Tripeptide-1                  
    • Nonapeptide-1        158563-45-2   
    • Palmitoyl Tetrapeptide-7   
    • Acetyl Tetrapeptide-5

Catalog Peptides

  • Acetalin ACTH and Related Peptide
  • Sequences Acyl Carrier Protein (ACP) Fragments
  • Adipokinetic Hormones
  • ADP-Ribosylation Factors (ARF)
  • Adrenomedullin Peptides
  • Agouti Related Peptides
  • Allatostatins Amylins (IAPP) 
  • Fragments Amyloid Peptides
  • Angiogenin and Related Peptides
  • Angiotensin and Related Peptides
  • Annexin Peptides
  • Anti-Inflammatory Peptides

Functional Peptides

Antimicrobial Peptides

Cell Penetrating Peptides

Chelate Peptides (DOTA related peptides)

MHC-Peptide Tetramer

Contact details:

Address: SUITE 115, 17 Ramsey Road, Shirley, NY 11967, USA

Tel: 1-631-624-4882

Fax: 1-631-614-7828

Email: info@creative-peptides.com

3. AAPPtec (Complete Peptide Product Source)

AAPPTec, LLC is an American peptide synthesis company located in Louisville, KY, that provides a complete line of peptide products ranging from automated peptide synthesizers to peptide-related laboratory equipment and high-quality reagents. AAPPTec peptide synthesis products help chemists prepare and analyze peptides in research for semi-preparative and preparative scale. We provide all the technical information and instructions for each step of peptide synthesis and purification. AAPPTec also offers custom peptides, for those who prefer not to synthesize their own peptides, in quantities from mg to kg, in purities from crude to 98% pure, all at an affordable price.

Projects they are working upon

Vaccines against the SARS-CoV-2 virus are just becoming available. While this is good news for controlling the spread of the virus, there has not been as much success in developing therapeutic agents for treating patients infected with SARS-CoV-2.  A significant amount of research is being published on laboratory studies and computer modeling to find peptides that may have potential therapeutic or diagnostic applications.  Below are some of the recently published papers concerning SARS-CoV-2.

Products:

Catalog Peptides

  • ACTH
  • Allatostatin
  • Amylin
  • Amyloid peptides
  • Angiotensins
  • Apelins
  • Bombsins
  • Bradykinins
  • Calcitonin and calcitonin precursors
  • CGRP
  • Cholecystokinin
  • Cone snail toxins
  • Corticotropin releasing factor
  • Cosmetic
  • Endothelins
  • Enkephalins and Enkephalin Analogs
  • Fibronectin Fragments and Analogs
  • Galanin
  • Gastric Inhibitory peptide
  • Gastrin and Gastrin releasing peptide
  • Glucagon and Glucagon like peptides
  • Growth hormone releasing factor
  • Interleukin Fragments
  • LHRH and GnRH
  • Lipotropin Fragments
  • Melanocyte stimulating hormones
  • Myelin Basic protein Fragments
  • Natriuretic peptides
  • Neurokinins Neuromedins and Preproneuromedins
  • Neuropeptide Y
  • Neurotensins
  • Opiods Peptides
  • PACAP
  • Pancreatic Polypeptide
  • Pharmaceutical
  • Protease Activated Receptors
  • Protease kinase related peptides
  • pTH,pTH related protein, Hyper calcemia malignancy Factors
  • Somatostatin
  • Substance P
  • Thrombin receptor activating peptide
  • TRH and preproTRH
  • Urocortin, Stresscopin and stresscopin related peptide
  • Vasopressin
  • VIP and preproVIP
  • Virus Protein Fragments

Custom Peptides

They provide custom synthesis of peptides based upon requirements.

Address: 6309 Shepherdsville Road Louisville, KY 40228

Tel: 502-968-2223

Fax: 502-968-3338

Email: sales@aapptec.com

4. INOTREM (control innate  immunity)

Inotrem is an advanced clinical stage biotech company specialized in immunotherapy to control dysregulated inflammatory reactions. The company proposes a new concept of controlling innate immunity that targets the TREM-1 pathway, an innate immune amplifier, to restore a balanced response in inflammatory diseases. Inotrem is developing nangibotide, a peptide and first-in-class TREM-1 inhibitor, with applications in severe conditions such as septic shock and COVID-19. Leveraging its proprietary technology platform, Inotrem is also conducting a broad monoclonal antibody program to target chronic inflammation, fibrotic diseases and immuno-oncology. Inotrem’s deep knowledge of the TREM-1 pathway biology and role in inflammation allows developing in parallel companion diagnostics tools to select those patients more likely to benefit from the anti-TREM strategies.

Projects

Inotrem targets the TREM-1 pathway as a key factor in unbalanced inflammatory responses. The company focuses on the therapeutic and diagnostic tools derived from its knowledge of the biology of the TREM-1 pathway. Inotrem has 2 late-stage clinical programs ongoing in acute inflammatory diseases such as septic shock and COVID-19 with its lead product nangibotideInotrem also targets chronic inflammatory diseases through a broad anti-TREM monoclonal antibody program.

Products

  • Nangibotide
  • Monoclonal Antibodies

Contact Details

Address: 54 rue de Ponthieu75008

Tel: +33 966817900

Email: contact@inotrem.com

5. AGC Biologics

AGC Biologics is a global CDMO providing pharmaceutical development and manufacturing services for protein-based biologics and cell and gene therapies. With seven facilities and teams of scientists across three continents, they have the resources and the available capacity you need to accelerate your race to GMP. From development to clinical trials, to full-scale commercialization, they can help you reach your goals at any stage in the drug development and manufacturing process. They specialize in the following modalities and substances, mammalian and microbial-based therapeutic proteins, recombinant DNA, plasmid DNA (pDNA), Messenger RNA (mRNA), viral vectors, and genetically engineered cells. Their services range from Process Development, Analytical Development and cGMP Manufacturing, Quality Control and Quality Assurance, and Process Validation. They forge exceptionally strong partnerships with our customers, and we never lose sight of our commitment to delivering reliable and compliant drug substances.

Projects they are working upon:

mRNA

AGC Biologics leveraged its 25+ years of experience in microbial, drug substance, and pDNA manufacturing to create our Messenger RNA (mRNA) service line. They manufacture high-quality mRNA for some of the most demanding applications in the industry today, offer customized process development services based on your specific mRNA and host system needs, and produce substances compliant with EMA & U.S. FDA standards. 

Their routine GMP manufacturing of proteins has helped us build one of the fastest-growing mRNA service offerings in the CDMO industry.

The expert teams at the Heidelberg, Germany site have extensive technical expertise in fermentation, purification, and analytics to help bring your next mRNA project to life. 

Products

  • Microbial

They have successfully expressed:

  • Antibody fragments
  • growth factors
  •  Antigens
  • Enzymes

Contact Details

Address: 21511 23rd Dr.SE Bothel WA 98021 USA

Tel: +1-425-485-1900

Email: contactus@agcbio.com

Fax: +1-426-486-0300

6. Bachem – The Perfect Ingredients for a Better World

Bachem is a leading, innovation-driven company specializing in the development and manufacture of peptides and oligonucleotides. The company, which has over 50 years of experience and expertise, provides products for research, clinical development and commercial application to pharmaceutical and biotechnology companies worldwide and offers a comprehensive range of services. Bachem operates internationally with headquarters in Switzerland and locations in Europe, the US and Asia. The company is listed on the six Swiss Exchange.

Products

  • Catalog Peptides
  • Cosmetic Peptides
  • Custom Peptides
  • Peptides NCES
  • Oligonucleotide NCES

Contact details:

Address: Bachem Americas, Inc.3132 Kashiwa Street Torrance, CA 90505 USA

Tel:  +1 888 422 2436, +1 888 4

BACHEM, +1 310 539 4171
Fax:  +1 310 539 9428
Email:  sales.us@bachem.com

7. GenScript  (Make Reseach Easy)

Genscript is the world’s leading biotech company providing life sciences services and products. With gene synthesis, peptide, protein, antibody and preclinical drug development service capabilities, they are internationally recognized as a leading biotech company specializing in fundamental life sciences research and early-phase drug discovery services. As of June 30, 2022, more than 74,700 peer-reviewed journal articles cited GenScript’s services and products, making GenScript the most frequently cited Biotech Company in the world.

Products                                  

Beta-Amyloid Peptides

  • Amylin
  • Beta amyloid

Cosmetic Peptides

  • Palmitoyl Tetrapeptide 3

Amino Acid Derivatives

COVID-19 Services and Products

The impact that the COVID-19 pandemic has had worldwide is of unprecedented proportions, with over 280 million infected and 5.4 million deaths in 224 countries and areas.

From diagnostics to drug discovery and vaccine development, GenScript has developed a comprehensive range of products and services that scientists can use to accelerate COVID-19/SARS-CoV-2 research and development.

Contact Details

Address: 860 Centennial Ave. Piscataway NJ 08854

8. American Peptide Company, Inc.

American Peptide Company, Inc., a Member of the Bachem Group (APC) maintains a wider range of skill sets for manufacturing peptides than any US manufacturer. APC designs protocols for producing bulk peptide in increasing scales and complexity including conjugations to proteins, toxoids, antifungals, KLH, and PEG. Our cGMP manufacturing facility in Vista, California is capable of any manufacturing scale required using solid-phase and solution chemistry. Our services include research, clinical and commercial scale production, assay development and validations, stability studies, and support for regulatory submissions, such as CMC’s and DMF’s. APC has a large non-GMP facility in Sunnyvale, California making custom and catalog peptides.

Products

  • Catalog Peptides
  • Cosmetic Peptides
  • Custom Peptides
  • Peptides NCES
  • Oligonucleotide NCES

Contact Details

Address: 1271 Avenida Chelsea Vista, CA 92081 USA

9. APi AmbioPharm, Inc

With peptide manufacturing and purification facilities in North Augusta, South Carolina and Shanghai, China, AmbioPharm has more than 600 chemists and professionals on staff.  As a GMP peptide CDMO focused on superior quality, both facilities are regularly audited and inspected by the FDA. Superior chemistry and facilities enable us to provide best-in-class quality with very reasonable costs of production.

Products

Generic Peptides

  • Bivalirudin
  • Buserelin
  • Carbetocin
  • Desmopressin
  • Elcatonin
  • Glucagon
  • Nesiritide
  • Triptorelin
  • Vasopressin

Cosmetic Peptides

Contact Details:

Address: Ambiopharm Inc. 1024 Dittman Ct, Beech Island, SC 29842, United States

Phone:  +1 (803) 442-7590

Fax: sales@ambiopharm.com

10. ASYMCHEM

At Asymchem they are proud of the strides that we have made since our founding in 1999, providing R&D and one-stop production services to the world’s top pharmaceutical companies. Driving their success is their commitment to continual optimization and investing in the future. By improving the capabilities their partners need now, and maintaining the agility needed to support innovation, they have built a knowledge and experience base that we’re ready to share. Whether they are supporting emerging biotech companies or smaller, specialty pharma, their mission remains to accelerate the launch of new drugs, providing one-stop CMC services for the full lifecycle of drug development. Their solutions range from early clinical stage to commercial stage, including R&D and cGMP production of advanced intermediates, APIs, formulations, as well as clinical research services. Through strategic partnerships and calculated business growth, they have built an integrated service ecosystem.

Projects they are working upon

Enzymes

Captive Production Ensures Ready Supply

Enzymes as biocatalysts have caught our attention in recent years. By building their own enzyme library, developing fast enzyme screening and evolution, enlarging fermentative production and even discovering the possible applications of immobilized enzymes in this industry, they are at the forefront of companies looking to commercialize the application of this technology.

Their high-throughput screening tools, robotics, and increase the number of enzymes they produce in house and take advantage of new methods for engineering new catalysts. They have made substantial investment in this area, because they know that by eliminating the need to obtain enzymes from a third-party, we simplify the supply chain while reducing costs for our customers. By producing enzymes actively, there’s no need for stabilizers and additional ingredients that only increase shelf life.

Products

  • Peptides
  • Oligonucleotides

Contact Details

Address: Asymchem Inc. 600 Airport Blvd, Suite 1000 Morrisville, NC 27560 USA
Tel: +1-919-897-8807

Email: information@asymchem.com

11. CSBIO

CSBio is a leading peptide and instrumentation manufacturing company located on the edge of
Silicon Valley in Menlo Park, California. Since 1993, CSBio has been providing high quality custom peptides, cGMP peptides and automated peptide synthesizers to the global pharmaceutical community. Their peptide products and instrumentation can be found in production laboratories and pharmaceutical companies worldwide.

Products:

  • cGMP Peptides
  • Peptide APIs
  • Non-Clinical Peptides
  • Peptide Resins and Amino Acids

Contact Details

Address: 20 Kelly Court Menlo Park, CA 94025

Tel:  (+650) 322 1111
Email:  peptides@csbio.com

12. CPC Scientific Peptide Company

Founded in 2001, CPC Scientific is a globally recognized peptide company and leading CDMO specializing in synthetic peptide production. They work directly with leaders in the biotechnology and pharmaceutical industries to help bring life-changing therapeutics and diagnostics to market. They boast the largest research peptide facility in the world, which successfully has undergone multiple FDA inspections and audits by global pharma organizations.

CPC Scientific has the capability of serving customers from early drug discovery stages through clinical trials to commercial manufacturing. They provide milligram to multi-kilogram quantities of CGMP and research-grade peptides with purities of up to 99%. With their emphasis on technology, innovation, and quality, we are proud to have a US FDA inspected GMP facility, ISO 9001, and ISO 13485 certification, a claim few companies in the world can make.

Products:

Generic Peptides

  • Bivalirudin
  • Buserelin
  • Cetrorelix
  • Exenatide
  • Leuprolide

Neoantigen Peptide

Custom Peptides

  • Peptide Stapling
  • Peptide Macrocycles
  • Click Peptides

Contact Details

Address: CPC Scientific Inc. 160 E Tasman Dr. Suite 200 San Jose, CA 95134

Phone: (408) 734-3800

Fax: (408) 734-3810

Email: sales@cpcscientific.com

13. P3 BioSystems

P3 breaks through the ordinary with quality and integrity unmatched in the field. Your research is far too important to trust just anyone, so consider making P3 Bio Systems your “Partner for Life”. Their chemical products are among the highest purities available. Each product is blind tested and confirmed for both identity and purity by an independent third party laboratory. They provide quality you can trust. With over 95% of our standard inventory products in stock and shipping the same day, you can trust that they have it when you need it.P3 has the most competitive products in the market. You may find a lower price, but not for a product of equal quality and purity. You can trust them to always provide the “best value”.

Products:

Custom Peptides

  • They provide custom synthesis of peptides based upon requirements.

Contact Details

Address: P3 BioSystems 10200 Forest Green Boulevard, Suite 112

Phone: 1-888-737-5598

Email: sales@p3bio.com

14. rPeptide (R & D starts here)

R&D starts at rPeptide – Whether it is to fill a research gap or have a scientific breakthrough, they are all striving towards a better tomorrow together. They are committed to helping scientists and researchers all over the world by providing high-quality products and exceptional service for Alzheimer’s, Parkinson’s, and other neurodegenerative research. They provide Integrity by staying true to who they are and their work ethic ensures that we produce the best quality products. Learning more about each other helps to provide the service their customers deserve. Staying curious and always learning about our customer’s needs and the latest research is their path to innovation. Uniting their passions and skills to provide our customers with everything they need to lead them to a healthier and brighter future.

Products

Peptides

  • Amylin
  • Beta-Amyloid
  • Amyloid Precursor
  • Protein Related Peptide

Contact Details

Address: 1050nBarber Creek. Bldg.300, Suite 103 Watkinsville, GA 30677, USA

Phone: 678-753-0747

Email: sales@rpeptide.com

List of Companies that are Manufacturing Peptide Supplements in USA

15. SMP (Supplement Manufacturing Partners)

The most modern machinery for nutraceutical manufacturing to produce even the largest orders quickly and efficiently. State of the art industrial HVAC systems keeping air filtered clean, humidity and temperature controlled. Three laboratories whose sole job is for cGMP-mandated raw material testing, label analysis and final product quality assurance. Quality of their raw ingredient suppliers and their relationship with them buying large quantities. Huge selection of in-stock products available for lower MOQ and competitive price points. Their unparalleled client relationship & services. Their mission at SMP is to treat their clients like partners in business which is why SMP stands for Supplement Manufacturing Partner. Your long term success is their long term success which is why they invested heavily into being able to scale and support your business.

Products

  • Capsules

Adrenal Support Vegan Capsules – Daily Health Complex – W/ Ashwagandha – Schisandra, B12 Methyl, Magnesium, Tyrosine & Much More – Non-GMO – Gluten Free

  • Tablets

L-Carnitine Tartrate Tablets 500 mg – Non-GMO – Gluten-Free

  • Gummy vitamins

4 In 1 Stress Relief Gummy – L-Theanine – Magnesium Citrate – Chamomile – Lemon Balm – Organic Tapioca Base – Allergen Free – Gluten Free – Non-GMO – Vegan Friendly

  • Jelly beans

Biotin Booster Jellybeans – 10,000MCG per Serving – Natural Strawberry Flavor – Non-GMO – Gluten Free – Vegan Friendly

  • Soft gels
  • Powders

Contact Details

Address: 250 Executive Drive, Unit L, Edgewood, NY, 11717

Phone: (833) 810-9896

16. Lifetein

LifeTein, located in Somerset, New Jersey, was founded in 2008 with a simple vision: understanding life sciences one protein at a time. This philosophy has formed the foundation of every peptide, protein, antibody, gene, and chemical project that we have completed for their customers in biotech, pharma, academia, government, diagnostics, and related organizations across the United States and in more than 30 other nations. They offer a wide range of custom peptide synthesis and conjugation services, custom protein, antibody and chemical services.

Products

Peptide Products

  • Biotin SBP1
  • Aviptadil
  • Protein A Magnetic Agarose Resin
  • Beta Amyloid

Contact Details

Address: LifeTein, 601 US. Rt.206, Suite 26-463 Hillsborough, New Jersey 08844 USA

Phone: 1-732-444-3282

Fax: 1-888-791-1618

Email: info@lifetein.com

17. SDC Nutrition Inc. Powder & Capsule Supplement Manufacturer in Pittsburgh, USA (Wellness and Fitness Services)

SDC nutrition was founded by having their protein powders manufactured by others, however after multiple contract manufacturing issues regarding delivery times, identity of products and others, SDC made the decision to manufacture all powder products, such as whey proteins, pre workouts and plant based proteins; in house to ensure quality. They offer these same services and turn key manufacturing practices that we take pride in for our own products for you as well. They know how important it is to deal with business partners and manufacturers you can trust who do what they say they will do and that’s the core of what they deliver.

Products

  • They provide custom synthesis of peptides based supplements upon requirements.

Contact Details

Address: 170 Industry Drive Pittsburgh, PA 15275 USA

Phone: (412) 275 – 3351

Email: info@sdcnutrition.com

18. Nutra Science Labs

The landscape of the dietary supplement industry has undeniably changed over the years, but the foundation of their company has withstood the test of time. Discover how their past shaped them into the award-winning nutraceutical manufacturers they are today and who they strive to become tomorrow.

Products

They provide custom synthesis of peptides based supplements upon requirements.

Contact Details

Address:  70 Carolyn Boulevard, Farmingdale, NY, USA 11735

Phone:  (631) 247-0660

19. Quality Supplements Mfg

Quality Supplement Manufacturing understands that having satisfied clients will make our company strong. QSM is a one-stop-shop for Formulation, Bottling, Encapsulation, Labeling, Packaging, and Tableting. The goals for QSM are providing the highest quality, faster delivery, and great prices. With their 1,000 ingredients of products in stock, Quality Supplement Manufacturing is the leader in Private Label Supplements and custom supplement manufacturing. As a supplement contract manufacturer, they specialize in providing companies with high-quality custom supplements with over 45 years of supplement manufacturing experience. They are an FDA-registered and cGMP-certified facility based in the USA.

Products

They provide custom synthesis of peptides based supplements upon requirements.

Contact Details

Address: 300 North MacArthur Blvd Oklahoma City, Oklahoma 73127

Phone: 1-888-458-3909

Email: Sales@QSManufacturing.com

20. MCE Pharma

They are a Czech company that develops and manufactures innovative food supplements, pet supplements and premixes of food or veterinary quality. They offer our food supplements and pet supplements, in the form of tablets and powders, under the mcePharma brand or as a private label, which we distribute worldwide. An integral part of their services is contract development and manufacturing of tablet and powder forms, they offer a complete service from concept to final product, including the production of small batches or stability studies.

Products

  • They provide custom synthesis of peptides based supplements upon requirements.
  • Food Supplements
  • Pet Supplements
  • Colostrum and Lactoferrin

Contact Details

Address: mcepharma s.r.o Boduvatelska 1178/35 Bilovec, 743 01 Czech Republic

Phone: +420 556 778 500

Fax: +420 597 579 513

Email: sales@mcepharma.com

21. Sky Nutro Manufacturing

They manufacture nutraceutical products, including including vitamins and supplement gummies, all natural private label beauty products or more.

Products

  • Tinctures and balms
  • Lotions
  • Soft gels
  • Nutraceutical products
  • They provide custom synthesis of peptides based supplements upon requirements.

Contact Details

Address: Sky Nutro LLC, 65 Moon St Southbridge MA 01550

Phone: 978-302-1868

Fax: 617-531-2090

Email: mike@skynutro.com

22. JPT Innovative Peptide Solutions

JPT Peptide Technologies GmbH is a leading provider of innovative peptide-based services, and catalog products & kits, as well as a research and development partner for projects in Immunology, Proteomics and Drug Discovery. JPT’s head office and production sites are located in Berlin, Germany. All of its production and services are performed in Berlin/ Germany in accordance with DIN EN ISO 9001:2015 guidelines. Together with its partner company JPT Peptide Technologies Inc. based in Acton, near Boston, Massachusetts, JPT is serving a worldwide customer base in the pharmaceutical and biotechnology industries, as well as researchers in universities, governmental and non-profit organizations. Over the past decade, JPT has developed a portfolio of proprietary technologies and a series of unique products and services which support research efforts in proteomics, all development phases of novel vaccines or immune therapies and peptides based drug discovery.

Projects they are working upon

Peptide Mimotope Optimization

Zolbetuximab (IMAB362) is a chimeric monoclonal antibody that showed promising results in the treatment of advanced CLDN18.2-positive gastric and gastro-oesophageal adenocarcinoma and is currently evaluated in phase III studies (Sahin et al. Ann. Oncol. 2021. PMID: 33610734).

Peptidic mimotopes for the ELISA-based detection of IMAB362 in biological samples were developed. Initial hits were identified using phage display and optimized with the help of structure-activity relationship analysis on peptide microarrays. The optimized peptides showed binding constants in the low nanomolar to picomolar range, an improvement by a factor of up to 30 compared to the initial hits. The best mimotope (apparent KD = 0.15 nM) was successfully used for the ELISA-based quantification of IMAB362 in samples from a mouse pharmacokinetic study.

Proteome Tools

Translating the Human Proteome into Molecular and Digital Tools for Drug Discovery, Personalized Medicine and Life Science Research

The verification of the correct assignment of fragment ion mass spectra to peptide sequences is still a challenge in mass spectrometry based proteomics. The preferred way to achieve this is the use of reference spectra of synthetic peptide standards. Within the Proteome Tools project we synthesized >1 million individual tryptic and non-tryptic, non-modified and modified peptides representing all human proteins and systematically created CID, HCD, ETD and EThcD spectra.

The libraries of peptides and spectra will greatly facilitate the validation of discovery proteomics data, will form a basis for targeted proteomic assays, enable FDR estimation in large datasets or repositories and help to better understand peptide fragmentation thus improving identification algorithms and spectra acquisition. Based on the data, new prototypes and products will be developed that form the basis for advancing research in a broad range of biomedical areas, like biomarker discovery, target validation, and drug discovery.

The project was funded by Bundesministerium für Bildung und Forschung (BMBF). 

Products

  • They provide custom synthesis of peptides based supplements upon requirements.
  • Clinical Peptides

Contact Details

Address: jPT peptide technologies GmbH Volmerstrasse 5 12489 Berlin, Germany

North America

Phone: 1.888.JPT.COMO (1.888.578.2666)

Fax: 1.888.JPT. COMO (1.888.578.2666)

Email: peptide@jpt.com

23. Paragon Laboratories

In 1971, the Kaufman family launched a dream:

To be a leader in custom manufacturing of nutritional supplements and Paragon Laboratories was born. From that humble beginning, Paragon has grown to be a major success and managed proudly by brothers Jay and Richard Kaufman. But there’s a big difference from those early days.
As science and technology have advanced, Paragon has not only kept up with them but has often been at the leading edge. With over 50 years in the contract manufacturing business, their team truly understands the industry, allowing us to implement best supplement manufacturing practices and provide insight into current trends.

Products

They provide custom synthesis of peptides based supplements upon requirements.

Contact Details

Address: 20433 Earl Street, Torrance, CA 90503

Phone: (800) 231-3670

Fax: (310) 370-7354

Email: sales@paragonlabsusa.com

24. NETQEM

NetQem is a reliable and experienced source for Custom Services, APIs & Specialty Chemicals Supply Service since 1997 to hundreds of companies in North America, Canada, Germany, France, United Kingdom, Italy, Austria, Japan…including well-known pharmaceutical and cosmetic companies, such as Abbott Laboratories, Aldrich, DuPont, Eli Lilly, Estee Lauder, Fisher Scientific, Merck, Schering-Plough,Virbac, VWR International, Wyeth, Zambon Group Italy. With strong research and production teams equipped with top quality facility and highly experienced chemists, NetQem can provide access to efficient, cost-effective custom synthesis on lab scale, pilot scale and commercial scale. They concentrate on Custom Manufacturing multi-step synthesis of pharmaceutical intermediates. NetQem is also a knowledgeable source for Contract Research Projects on discovery of novel, complex compounds, synthesis of various derivatives, analogs, substitutions of building blocks, and building a library of compounds in the form of the project based or FTE. In addition, they provide Process Development Services from scale-up to Kilo-Lab, Pilot Plant and finally Production scale. All projects and inquiries are managed in the strictest of confidence.

Products

  • NetQem can provide access to efficient, cost-effective custom synthesis on lab scale, pilot scale and commercial scale.
  • Nutritional Supplemental
  • Phytochemicals and Natural Products

Contact Details

Address:  2530 Meridian Parkway, Suite 300, Research Triangle Park, NC 27713, USA

 P.O. Box 12091, Research Triangle Park, NC 27709

Phone: (919)544-4122

Fax: (919)544-4109

Email: sales@netqem.us 

25. Centerchem

Centerchem is an important global supplier of quality functional specialty ingredients used in a wide range of technology-based industries. Its history in the United States dates back to 1948, when it began as a marketer of naturally derived substances. Tracing its roots to Europe over a century ago, Centerchem today has become a leading international marketer of unique functional products for use in the cosmetic, food, pharmaceutical ingredients, flavors, and fine chemical industries.

Representing a broad range of domestic and international companies for many years, Centerchem’s strengths remain in its dedication to maintaining high-quality support of its customers within all of its diverse business areas. This capability can be directly traced to Centerchem’s highly specialized technical personnel, the numerous technologies to which it has access, and the internal resources that are essential to remaining competitive in today’s global environment.

But first and foremost, Centerchem’s main focus is in the commercialization of new technology. In this role, it has maintained a network of contacts and specialty manufacturers throughout the world, which continue to furnish customers (domestic and international) with unique functional chemical raw materials. Together with its own internal technical market research and promotional expertise, its strategically located inventory points, and thorough knowledge of transportation regulations, these capabilities are why Centerchem remains a leader in its field. Special performance requirements place special demands on raw materials for the food industry. Centerchem’s ingredients and technical support capabilities have successfully responded to the critical manufacturing needs of clients seeking to market quality consumer food products.

Products

  • They provide custom synthesis of peptides based supplements upon requirements.

Contact Details

Address: 20 Glover Avenue Norwalk, CT 06850

Phone: (203) 822.9800

Fax: (203) 822.9820

Email: orders@centerchem.com

26. Emisphere Technologies, Enhancing Oral Formulations of Large and Polar APIs

Emisphere Technologies is a drug delivery company that develops improved oral formulations of poorly permeable APIs such as peptides, proteins, oligonucleotides and polysaccharides, as well as polar small molecules. Emisphere Technologies is a drug delivery company that develops improved oral formulations of poorly permeable active pharmaceutical ingredients (API) such as peptides, proteins, oligonucleotides, and polysaccharides, as well as polar small molecules.

Emisphere launched its first commercial product using their proprietary delivery system, Eligen Technology in March 2015.

Projects they are working upon

Oral delivery enhancement of large and polar APIs

Emisphere has developed a unique technology for enhancing the oral delivery of drugs that are normally given by injection or have poor oral bioavailability because their permeability through cell membranes is inadequate. Eligen Technology has brought more than half a dozen oral formulations of peptides normally given by injection such as GLP-1 and insulin into clinical development. In addition, oligosaccharides, polar small molecules and even metals have been shown to have significant increases in oral bioavailability in the clinic.

Products

  • Eligen B12™ is a once-daily oral non-prescription medical food shown to normalize B12 levels without the need for an injection.

Contact Details

Address: 4 Becker Farm Road Suite 103, Roseland, 07068, New Jersey, United States of America

Phone: +1 973 532 8000

Fax: +1 973 422 0125

Email: csailer@emisphere.com

27. Alkeremes Inc.

Alkermes is focused on developing innovative medicines that aim to address unmet needs of people living with serious mental illness, addiction and cancer. As a fully-integrated global biopharmaceutical company, we apply our scientific expertise and proprietary technologies to develop products that are designed to make a meaningful difference in the way people manage their diseases.

Beyond our central mission to develop medicines, we believe in championing approaches to treatment that account for the multitude of factors that affect outcomes for patients, caregivers and communities. In addition to our scientific pursuits, we are committed to patient engagement, disease education and awareness and advocacy for important policies that support equitable access to treatment options.

We believe that being a positive force for change begins when we dare to expect more – of medicines, of our healthcare system and of ourselves – as we seek to reset expectations of what constitutes successful management of complex diseases.

Projects they are working upon

Their research and development efforts are focused on the pursuit of potential new medicines that build on their heritage in neuroscience and, as scientific opportunities present themselves, advancement of our research into important new areas such as immuno-oncology.

Serious Mental Illness

We are committed to addressing unmet needs in serious mental illness through the development of therapeutic options to support adults living with schizophrenia and bipolar I disorder.

Products

  • They provide custom synthesis of peptides based supplements upon requirements.

Contact Details

Address: 265 Olinger Circle Wilmington, OH 45177 , United States of America

Phone: +1 937 382 5642

Email: suppliersupport@alkermes.com

References

  1. https://www.google.com/search?q=BOC+science+peptide+products
  2. https://www.creative-peptides.com/
  3. https://www.peptide.com/custom-peptide-company
  4. https://www.inotrem.com/
  5. https://www.agcbio.com/
  6. https://www.bachem.com/
  7. https://www.genscript.com/
  8. http://www.americanpeptide.com/
  9. https://www.ambiopharm.com/
  10. https://www.asymchem.com/
  11. https://www.csbio.com/
  12. https://cpcscientific.com/
  13. https://p3bio.com/
  14. https://www.rpeptide.com/
  15. https://www.smpnutra.com/
  16. https://www.lifetein.com/
  17. https://sdcnutrition.com/
  18. https://www.nutrasciencelabs.com/
  19. https://qualitysupplementmfg.com/
  20. https://www.mcepharma.com/
  21. https://skynutro.com/
  22. https://www.jpt.com/
  23. https://www.paragonlabsusa.com/
  24. http://www.netqem.us/
  25. https://www.centerchem.com/
  26. www.emisphere.com
  27. https://www.alkermes.com/
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